Regulation of Telomere Length by Fatty Acid Elongase 3 in Yeast
نویسندگان
چکیده
منابع مشابه
Two Modes of Regulation of the Fatty Acid Elongase ELOVL6 by the 3-Ketoacyl-CoA Reductase KAR in the Fatty Acid Elongation Cycle
Fatty acids (FAs) are diverse molecules, and such diversity is important for lipids to exert their functions under several environmental conditions. FA elongation occurs at the endoplasmic reticulum and produces a variety of FA species; the FA elongation cycle consists of four distinct enzyme reactions. For this cycle to be driven efficiently, there must exist coordinated regulation of protein ...
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The products of yeast fatty acid synthetase, under usual assay conditions, are palmitate (60%) and stearate (40%). Addition of stearyl-CoA decreases synthetase activity and increases relative amounts of stearate formed (-64%). The ratio of palmitate to stearate produced is also altered by changing the incubation temperatures. At temperatures of 30°C or above, the ratio of palmitate to stearate ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2008
ISSN: 0021-9258
DOI: 10.1074/jbc.m802980200